The Science

The Science
Evidence-based. Not opinion-based.

Every optimal range, every intervention, and every recommendation in an atry report is grounded in peer-reviewed clinical literature. Not wellness trends. Not anecdote. Not population averages.

The difference matters. Standard lab reference ranges are built from a sample of the general population, then set at the 95th percentile of that sample — they tell you whether you're statistically typical, not whether you're operating at your best. Our framework uses optimal ranges drawn from specialist clinical literature to identify where performance, longevity, and wellbeing are being compromised — often in people whose results look “normal”.

Blood sample vial, macro detail

Peer-reviewed reference ranges

Every optimal range in our framework is drawn from published clinical research and specialist literature — not population averages. We flag the gap between “in range” and truly optimal, and explain it clearly.

90+ marker intelligence framework

Our biomarker framework covers 90+ markers across metabolic, cardiovascular, hormonal, inflammatory, nutritional, and cognitive health domains — each with documented upstream and downstream relationships.

Intervention protocols from clinical evidence

Every nutritional, supplemental, and lifestyle intervention has a documented evidence base. Dosages, timing, and expected outcomes reference published trial data — not anecdote or generic advice.

Why testing conditions change your results

Several markers are highly sensitive to recent training, not just underlying health. Multiple studies on distance runners show liver enzymes (ALT, AST) and creatine kinase rising sharply in the hours after sustained exercise — in one study, AST rose 15-fold and ALT nearly 4-fold during a 200km ultramarathon. None of this reflects a health problem; it reflects recent physical activity. This is exactly why our intake process asks about training in the 48 hours before your draw — see How It Works for the full pre-test guide.

Runner training at dusk, atry health co

Markers we assess

A complete atry Biomarker Review covers markers across the following domains where present in your panel:

atry Health OS dashboard on laptop screen
MetabolicGlucose, HbA1c, fasting insulin, insulin resistance (HOMA-IR)
CardiovascularTotal cholesterol, LDL-C, HDL-C, triglycerides, ApoB, Lp(a), homocysteine, hs-CRP
HormonalTestosterone (total & free), SHBG, estradiol, DHEA-S, thyroid panel, prolactin
NutritionalVitamin D, B12, ferritin, magnesium, zinc, iron
Liver & kidneyALT, AST, GGT, creatinine, eGFR, bilirubin
Immune & inflammatoryCRP, ESR, white cell differentials
Cognitive & longevityIGF-1, cortisol
Body compositionContextualised against lifestyle, training, and nutrition inputs